15-deoxy-isoxeniolide-A, new diterpenoid from a bornean soft coral, Xenia sp.

作者：Phan Chin Soon; Kamada Takashi; Kobayashi Kazushi; Hamada Toshiyuki; Vairappan Charles Santhanaraju^*

来源：Natural Product Research, 2018, 32(2): 202-207.

DOI：10.1080/14786419.2017.1346638

• Soft coral
• Xenia sp
• xenicane
• diterpene
• adult T-cell leukaemia
• S1T

A new xenicane diterpenoid, 15-deoxy-isoxeniolide-A (1) along with four known compounds 9-deoxy-isoxeniolide-A (2), isoxeniolide-A (3), xeniolide-A (4) and coraxeniolide-B (5) were isolated from the Bornean soft coral Xenia sp. The structures of these metabolites were elucidated on the basis of spectral analysis, NMR and HRESIMS. Compound 5 showed cytotoxic activity against ATL cell line, S1T.

• 出版日期2018