科研之友
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摘要
Reduction of N-alkyl-2-(2-hydroxy-2-phenylethyl) pyridinium salts using excess of sodium triacetoxyborohydride afforded exclusively the corresponding tetrahydropyridine derivative bearing a piperidine ring with a double bond in the 3,4-position. Furthermore, under these conditions, syn-1,3-amino alcohols were obtained in good yield and diastereoselectivity.
- 出版日期2010-7
