Approaches to enhancing the sensitivity of capillary electrophoresis methods for the determination inorganic and small organic anions

作者：Breadmore MC; Haddad PR^*

来源：Electrophoresis, 2001, 22(12): 2464-2489.

• on-line preconcentration
• stacking
• solid-phase extraction
• capillary electrophoresis
• review

One of the major problems facing the development of capillary electrophoresis (CE) is the relatively high limits of detection when compared to traditional high-performance liquid chromatographic (HPLC) methods. While the use of an alternative detector can offer better sensitivity, a more universal approach is sample preconcentration. Numerous on-line methods have been developed to improve the sensitivity of CE, and are based on electrophoretic principles, chromatographic principles, or a combination of both. This review will discuss all forms of on-line preconcentration methods for CE, with emphasis given to those that have shown particular merit when applied to inorganic and small organic anions.

• 出版日期2001-8