A Cu(II) coordination polymer-based catalytic sensing system for detecting cysteine and sulfur anions

作者：Sun, Xiang-Ying^*; Qin, Zhen-Fa; Shen, Jiang-Shan; Cao, Xue-Gong; Liu, Bin; Wang, Huai-Qian

来源：Analytical Methods, 2018, 10(36): 4387-4393.

DOI：10.1039/c8ay01480a

• PEROXIDASE-LIKE ACTIVITY
• HYDROGEN-PEROXIDE
• SILVER NANOPARTICLES
• GLUCOSE DETECTION
• FLUORESCENT
• MECHANISM
• HEMIN
• WATER
• 3,5,3,5-TETRAMETHYLBENZIDINE
• HOMOCYSTEINE

Developing metal coordination polymer (CP)-based artificial enzyme mimics for establishing novel bio-chemosensing systems is important due to their high catalytic activity. Herein, a Cu(ii)-based CP (Cu-aspartic acid CP, that is Cu-Asp CP) was successfully prepared by a simple interface growth method. It was found that the as-prepared Cu-Asp CP has excellent peroxidase-like activity for 3,3,5,5-tetramethylbenzidine (TMB) as the substrate in the presence of H2O2. On the basis of these findings, taken together with high complexing stability constants between Cu2+ ions and cysteine (Cys)/S2- anions, simple, highly sensitive and selective colorimetric assays for detecting Cys and S2- anions were successfully developed, with low limits of detection estimated to be 0.625 mu M and 0.206 mu M, respectively.

• 出版日期2018-9-28
• 单位华侨大学