New eremophilenolactones from Senecio nemorensis

作者：Meng, Fan-Jun^*; Zhao, Hong; Xie, Wei-Doug; Zhao, Rui-Jian; Lai, Peng-Xiang; Zhou, Yan-Xia; Miao, Yan-Li

来源：Helvetica Chimica Acta, 2007, 90(11): 2196-2200.

DOI：10.1002/hlca.200790227

• PYRROLIZIDINE
• SESQUITERPENE
• ALKALOIDS
• LACTONES

Three new eremophilane sesquiterpenes were isolated from the MeOH extract of the roots of Senecio nemorensis. Their structures were identified as 8 alpha-hydroxy-6 ss-(isobutanoyloxy)-1-oxoeremophila-7(11).9-dieno-12.8 ss-lactone (1), 6 ss,8 ss-dimethoxy-1-oxoeremophila-7(11),9-dieno-12,8 alpha-lactone (2) and 10 alpha-hydroxy-6 ss-(isobutanoyloxy)-1-oxocremophila-7(11),8-dieno-12,8-lactone (3), respectively, based on spectroscopic data, including IR. EI-MS, HR-ESI-MS, and 1D- and 2D-NMR data.

• 出版日期2007
• 单位山东大学