Diets containing corn naturally contaminated with deoxynivalenol reduces the susceptibility of rainbow trout (Oncorhynchus mykiss) to experimental Flavobacterium psychrophilum infection

作者：Ryerse Ian A; Hooft Jamie M; Bureau Dominique P; Hayes M Anthony; Lumsden John S^*

来源：Aquaculture Research, 2016, 47(3): 787-796.

DOI：10.1111/are.12537

• deoxynivalenol
• rainbow trout
• corn
• Flavobacterium psychrophilum
• coldwater disease

The objective of this study was to determine if deoxynivalenol (DON) exposure alters the susceptibility of rainbow trout to bacterial coldwater disease caused by Flavobacterium psychrophilum. Rainbow trout were fed a nutritionally complete diet containing corn that was naturally contaminated with DON at a desired concentration of <0.5 (control and pair-fed treatments), 4 or 6ppm over 7weeks to apparent satiation. After 4weeks, fish were infected by intraperitoneal injection with F. psychrophilum (3.03x10(6)CFUmL(-1)) via intraperitoneal injection and monitored for morbidity and mortality. A significant linear reduction in feed intake was associated with increasing dietary levels of DON contamination over the initial 4weeks. There was a significant reduction (P<0.05) in cumulative per cent mortality in DON-fed groups (4.1ppm, 11%; 5.9ppm, 7%) in comparison to control (46%) and pair-fed (25%) groups at 21 days post infection. Mortality of trout pair-fed the control diet was also significantly lower (P<0.05) than the control group fed to apparent satiation. A replicate trial using genetically similar fish and the same experimental design produced similar results. These results suggest that DON exposure and restricted feed intake provided a protective effect for rainbow trout infected with F. psychrophilum.

• 出版日期2016-3