An influence of adrenaline (1:80,000) containing local anesthesia (2% Xylocaine) on glycemic level of patients undergoing tooth extraction in Riyadh

作者：Khawaja Naveed A^*; Khalil Hesham; Parveen Kauser; Alghamdi Ahmad M; Alzahrani Ra' ed A; Alherbi Sa' ad M

来源：Saudi Pharmaceutical Journal, 2014, 22(6): 545-549.

DOI：10.1016/j.jsps.2014.02.006

• Adrenaline
• Xylocaine local anesthesia
• Glycemic level
• Tooth extraction

Objective: Aim is to compare the glycemic level among patients before, and after local anesthesia containing adrenaline 1: 80,000 among patients who need dental extraction. %26lt;br%26gt;Materials and methods: 60 patients were randomly selected including 30 healthy and 30 with a diabetes history for this study in Riyadh city. First the blood glucose level was measured before administering local anesthesia containing adrenaline after taking their history with glucocheck according to instructions, then blood Sugar level was recorded after administering local anesthesia containing adrenaline 1:80,000 concentrations. Blood sugar level was also checked 5 min after the tooth extraction procedure. %26lt;br%26gt;Results: There were no significant results found after the administration of local anesthesia containing adrenaline in both healthy and diabetic patients (p %26gt; 0.05). However, change of significance (p %26lt; 0.05) was noticed in diabetic patients who had not taken their hypoglycemic medication; there was a rise in their blood glucose level after extraction. %26lt;br%26gt;Conclusion: The study concluded no significant effect on the glycemic level of patients after the administration of local anesthesia containing adrenaline 1:80,000 in healthy and diabetic patients whether hypoglycemic medication was taken or not but a rise in blood sugar level was found among diabetic patients who did not take their hypoglycemic medications undergoing tooth extraction.

• 出版日期2014-12