A multivariate curve resolution approach to separate UV-vis scattering and absorption contributions for organic nanoparticles

作者：Debus Bruno; Vitale Raffaele; Sasaki Shino; Asahi Tsuyoshi; Sliwa Michel; Ruckebusch Cyril

来源：Chemometrics and Intelligent Laboratory Systems, 2017, 160: 72-76.

DOI：10.1016/j.chemolab.2016.11.011

• Scattering
• Absorption
• Organic nanoparticles
• Two-dimensional correlation spectroscopy (2D-COS)
• Multivariate curve resolution-alternating least squares (MCR-ALS)

In this paper, the combination of Two-Dimensional COrrelation Spectroscopy (2D-COS) and Multivariate Curve Resolution Alternating Least Squares (MCR-ALS) is proposed to disentangle absorption and scattering contributions from extinction spectra collected during the synthesis of organic nanoparticles by laser ablation. This procedure relies on the fact that these contributions exhibit distinct dynamics in the synchronous and asynchronous modes of 2D-COS as the ablation proceeds. Thus, initial estimates for absorption and scattering spectral features can be discriminated and subsequently used when applying MCR-ALS analysis. The feasibility and the potential of this approach are demonstrated on a set of extinction spectra collected at different time intervals during the synthesis of dendronized perylenediimide (DPDI) nanoparticles. The time-dependent concentration profiles and spectra obtained provide valuable insights into the relative dynamics of its absorption and scattering. These results allow discussing the formation mechanism of DPDI nanoparticles.

• 出版日期2017-1-15