Does CYP2C19 genotype affect clinical outcome?

作者:ten Berg Jurrien M*; Deneer Vera H
来源:Nature Reviews Cardiology, 2012, 9(4): 192-194.
DOI:10.1038/nrcardio.2012.29

摘要

Commenting on the results of their meta-analysis, Holmes et al. suggest that CYP2C19 genotype does not affect clinical outcome in patients receiving clopidogrel therapy. However, we do not believe that the data support this conclusion; an association between genotype and outcome remains plausible and could be considered when choosing treatment.

  • 出版日期2012-4