Phloroglucinols from the Argentine Ferns Elaphoglossum gayanum and E-piloselloides

作者:Socolsky Cecilia; Borkosky Susana A; Hernandez de Teran Marcela; Asakawa Yoshinori; Bardon Alicia*
来源:Journal of Natural Products, 2010, 73(5): 901-904.
DOI:10.1021/np1000208

摘要

Five new prenylated phloroglucinols were isolated from the diethyl ether extracts of the ferns Elaphoglossum gayanum and E. piloselloides. Their structures were established by analysis of their spectroscopic data (ID and 2D NMR, HRMS, and IR) and chemical derivatization. The two major compounds exhibited moderate molluscicidal activity against the snail Biomphalaria peregrina, a vector of the tropical disease schistosomiasis, with LD(50) 7.2 mu g/mL (14.4 mu M) and 11.7 mu g/mL (22.2 mu M).

  • 出版日期2010-5