Differentiating Inherited Human Herpesvirus Type 6 Genome from Primary Human Herpesvirus Type 6 Infection by Means of Dried Blood Spot from the Newborn Screening Card

作者：Strenger Volker^*; Pfurtscheller Klaus; Wendelin Gerald; Aberle Stephan W; Nacheva Elisabeth P; Zoehrer Bettina; Zenz Werner; Nagel Bert; Zobel Gerfried; Popow Kraupp Therese

来源：Journal of Pediatrics, 2011, 159(5): 859-861.

DOI：10.1016/j.jpeds.2011.06.032

To differentiate active human herpesvirus type 6 (HHV-6) infection from inherited HHV-6 (iHHV-6), we analyzed dried blood spots from archived newborn screening cards in 3 patients with high HHV-6 DNA copy numbers. Two patients were positive for HHV-6 DNA as neonates suggesting iHHV-6. In 1 patient, the absence of HHV-6 DNA excluded iHHV-6. (J Pediatr 2011;159:859-61)

• 出版日期2011-11