Approach to the treatment of multiple myeloma: a clash of philosophies

作者:Rajkumar S Vincent*; Gahrton Gosta; Bergsagel P Leif
来源:Blood, 2011, 118(12): 3205-3211.
DOI:10.1182/blood-2011-06-297853

摘要

In this Perspective, we summarize some of the most contentious issues surrounding diagnosis and treatment of myeloma. We outline how a fundamental clash of philosophies, cure versus control, may be at the heart of many of the controversies. From the very definition of the disease to risk stratification to the validity of current clinical trial endpoints, we highlight the major areas of debate and provide alternative viewpoints that have implications for trial design and interpretation, as well as clinical practice. (Blood. 2011;118(12):3205-3211)

  • 出版日期2011-9-22