Nanomaterials and nanoclusters based on DNA modulation

作者：Fu, Yan; Wang, Xian; Zhang, Jinli; Li, Wei^*

来源：Current Opinion in Biotechnology, 2014, 28: 33-38.

DOI：10.1016/j.copbio.2013.10.014

• G-QUADRUPLEX
• NUCLEIC-ACID
• I-MOTIF
• CONFORMATIONAL-CHANGES
• GROWTH MECHANISMS
• POLYMORPHIC DNA
• NANOSTRUCTURES
• PH
• COMPETITION
• SYSTEM

Besides the inherent chirality, DNA is enriched by nitrogen and oxygen functional groups that are preferential to coordinate with transition metal ions, and its self-assembled structures, including the G-quadruplex, the i-motif, and the conventional Watson-Crick duplex, etc., can be adjusted via different base pairings. Recently biotemplating on the basis of DNA self-assembly has been considered as an attractive method to construct switchable nanomaterials, to direct crystal growth and to design enantioselective selectors/catalysts. This review briefly covers the recent progress relevant to DNA modulated nano/subnano materials. The long-term goal of this area of research is to explore novel promisingly environmental-benign approaches to construct switchable nanomachines, nano/subnano clusters and enantioselective recognition platforms respectively, through DNA-based modulation.

• 出版日期2014-8
• 单位天津大学