New recipes for biocatalysis

作者:Brustad Eric M*
来源:Nature Chemical Biology, 2014, 10(3): 170-171.
DOI:10.1038/nchembio.1457

摘要

The bacterial halogenase SyrB2 catalyzes selective installation of halogens in place of unactivated aliphatic C-H bonds. By substituting halide reagents with the nitrogenous anions N-3(-) and NO2-, SyrB2 can perform C-N bond formation reactions not previously observed in nature.

  • 出版日期2014-3

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