Measurement of multispectral scattering properties in mouse brain tissue

作者:Min Eunjung; Ban Sungbea; Wang Yanyan; Bae Sung Chul; Popescu Gabriel; Best Popescu Catherine*; Jung Woonggyu
来源:Biomedical Optics Express, 2017, 8(3): 1763-1770.
DOI:10.1364/BOE.8.001763

摘要

We present the scattering properties of mouse brain using multispectral diffraction phase microscopy. Typical diffraction phase microscopy was incorporated with the broadband light source which offers the measurement of the scattering coefficient and anisotropy in the spectral range of 550- 900 nm. The regional analysis was performed for both the myeloarchitecture and cytoarchitecture of the brain tissue. Our results clearly evaluate the multispectral scattering properties in the olfactory bulb and corpus callosum. The scattering coefficient measured in the corpus callosum is about four times higher than in the olfactory bulb. It also indicates that it is feasible to realize the quantitative phase microscope in near infrared region for thick brain tissue imaging.

  • 出版日期2017-3-1