Molecular radiobiology meets clinical radiation oncology

作者:Firat Elke; Heinemann Felix; Grosu Anca Ligia; Frommhold Hermann; Niedermann Gabriele*
来源:International Journal of Radiation Biology, 2010, 86(3): 252-259.
DOI:10.3109/09553000903419320

摘要

Background The 2nd Langendorff Congress in Freiburg in Breisgau (Germany) gathered basic and translational scientists 9 as well as clinicians interested in recent developments in molecular and clinical radiobiology The topics ranged from the most recent insight into the organisation of the DNA damage response and radiotherapeutically relevant cell death mechanism to biological imaging for treatment planning and advances in the understanding of the molecular biological effects of particle beams. Clinical aspects of stem cell and tumour stem cell biology as well as of angiogenesis and hypoxia, the search for novel molecular radiosensitisers and potential strategies for exploitation of the immune system to further improve tumour radiotherapy were also discussed.
Results and conclusion This report surveys the presentations at the meeting, considering their significance in light of the literature, and documents the increasing importance of molecular radiobiology for clinical radiooncology.

  • 出版日期2010-3