A light-up endoplasmic reticulum probe based on a rational design of red-emissive fluorogens with aggregation-induced emission

作者：Zhang Chong Jing; Cai Xiaolei; Xu Shidang; Zhan Ruoyu; Jien Wu; Liu Bin^*

来源：Chemical communications, 2017, 53(78): 10792-10795.

DOI：10.1039/c7cc05205g

Fine-tuning electron acceptors through changing one cyano group to an amide generates a more stable and emissive fluorophore with the character of aggregation-induced emission. Conjugation between the new fluorophore and CFFKDEL generated an excellent ER targeting light-up probe with high specificity and good photostability.

• 出版日期2017-10-7