An induction heating device using planar coil with high amplitude alternating magnetic fields for magnetic hyperthermia

作者：Wu, Zuhe; Zhuo, Zihang; Cai, Dongyang; Wu, Jian'an; Wang, Jie; Tang, Jintian^*

来源：Technology and Health Care, 2015, 23(s2): S203-S209.

DOI：10.3233/THC-150955

• Magnetic hyperthermia
• magnetic nanoparticles
• planar coil
• power abortion
• induction heating

BACKGROUND: Induction heating devices using the induction coil and magnetic nanoparticles (MNPs) are the way that the magnetic hyperthermia is heading. @@@ OBJECTIVE: To facilitate the induction heating of in vivo magnetic nanoparticles in hyperthermia experiments on large animals. @@@ METHODS: An induction heating device using a planar coil was designed with a magnetic field frequency of 328 kHz. The coil's magnetic field distribution and the device's induction heating performance on different concentrations of magnetic nanoparticles were measured. @@@ RESULTS: The alternating magnetic field produced in the axis position 165 mm away from the coil center is 40 Gs in amplitude; magnetic nanoparticles with a concentration higher than 80 mg. mL-1 can be heated up rapidly. @@@ CONCLUSION: Our results demonstrate that the device can be applied not only to in vitro and in small animal experiments of magnetic hyperthermia using MNPs, but also in large animal experiments.

• 出版日期2015
• 单位清华大学