Delayed cord clamping and blood flow in the superior vena cava in preterm infants: an observational study

作者：Meyer Michael P^*; Mildenhall Lindsay

来源：Archives of Disease in Childhood - Fetal and Neonatal Edition, 2012, 97(6): F484-F486.

DOI：10.1136/adc.2010.199703

Objective To determine if timing of cord clamping affects blood flow in the upper body, as measured by flow in the superior vena cava (SVC). %26lt;br%26gt;Design Observational study. %26lt;br%26gt;Setting Neonatal Unit, Middlemore Hospital, Auckland, New Zealand. Patients 30 preterm infants %26lt;30 weeks%26apos; gestational age. %26lt;br%26gt;Intervention Cord clamping was immediate in 17 infants and delayed by 30-45 s in 13. %26lt;br%26gt;Results Infants in the two groups did not differ significantly in terms of gestational age, gender or use of antenatal steroids. Median flow in the SVC in the first 24 h was significantly higher in the group with delayed clamping (median 91 ml/kg/min; IQR 81-101) compared with 52 ml/kg/min (IQR 42-100) in the immediate clamping group (p=0.028). Fewer infants in the delayed group had low flow (1 compared with 9; p=0.017). All three infants with intraventricular haemorrhage (IVH) (of any grade) had low flow. %26lt;br%26gt;Conclusions Blood flow in the SVC was higher in infants where delayed cord clamping was performed. The relationship of IVH, low flow and timing of cord clamping requires further study.

• 出版日期2012-11