Memory-Induced Chaos in Cardiac Excitation

作者:Landaw Julian; Garfinkel Alan; Weiss James N; Qu Zhilin*
来源:Physical Review Letters, 2017, 118(13): 138101.
DOI:10.1103/PhysRevLett.118.138101

摘要

Excitable systems display memory, but how memory affects the excitation dynamics of such systems remains to be elucidated. Here we use computer simulation of cardiac action potential models to demonstrate that memory can cause dynamical instabilities that result in complex excitation dynamics and chaos. We develop an iterated map model that correctly describes these dynamics and show that memory converts a monotonic first return map of action potential duration into a nonmonotonic one, resulting in a period-doubling bifurcation route to chaos.

  • 出版日期2017-3-28