科研之友
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摘要
Long-term prognosis for advanced stages of cutaneous T-cell lymphoma may be beneficially altered with the use of multimodality therapy. However, refractory disease exists in Which current therapeutic options fail to halt the progression of disease. We present 3 cases of refractory Sezary syndrome in which the combination of vorinostat and interferon gamma was well tolerated and produced significant clinical improvement. The potential immunologic basis for this is discussed. (J Am Acad Dermatol 2009;61:112-6.)
- 出版日期2009-7
