科研之友
微信
新浪微博
Facebook
分享链接
摘要
Small libraries of 3,5-unsubstituted 4-substituted-6-aryl-3,4-dihydropyridin-2(1H)-ones derivatives were synthesized from the condensation-products of aldehydes with Meldrum's acid, aromatic ketones and ammonium acetate using acetic acid as energy transferring-agent under microwave irradiation without catalyst. This method has the advantages of excellent yields (65-90%), short reaction time (5-10 min) and being environmentally friendly. It aimed to provide new series of potential biologically active compounds for biomedical screening.
- 出版日期2007-8
- 单位江苏师范大学
