A convenient one-pot synthesis of series of 3-(2,6-diphenyl-4-pyridyl)hydroquinolin-2-one under microwave irradiation and their antimicrobial activities

作者：Ladani Niraj K; Patel Manish P; Patel Ranjan G^*

来源：Indian Journal of Chemistry - Section B: Organic and Medicinal Chemistry , 2009, 48(2): 261-266.

• Microwave irradiation
• 2-chloro-3-formyl quinoline
• acetophenone
• N-phenacylpyridinium chloride
• Krohnke's reaction condition

A series of 3-(2,6-diphenyl-4-pyridyl)hydroquinolin-2-one 4a-x compounds arc synthesized in high yields by one pot cyclocondensation reactions under Krohnke's reaction conditions using 2-chloro-3-formyl quinoline 1a-d, various acetophenone 2a-f, N-phenacylpyridinium chloride 3 in the mixture of ammonium acetate and acetic acid by microwave irradiation. All the compounds have been characterized by elemental analysis, FT-IR, (1)H and (13)C NMR, and mass spectral analysis. These compounds have been screened for their antimicrobial activities.

• 出版日期2009-2