Anemia and bleeding in thrombocytopenic patients

作者:Carson Jeffrey L*; Stanworth Simon J
来源:Blood, 2017, 130(10): 1178-1179.
DOI:10.1182/blood-2017-07-795922

摘要

One might not have anticipated that lower hematocrit level is associated with bleeding in patients with hypoproliferative thrombocytopenia as suggested in a secondary analysis by Uhl et al in this issue of Blood.(1) However, patients with hematocrit <= 25% were reported to have a fivefold higher risk of grade >= 3 bleeding (odds ratio [OR], 5.09; 95% confidence interval [CI], 2.65-9.79) and a 1.2-fold higher risk of grade >= 2 bleeding (OR, 1.20; 95% CI, 1.03-1.39) compared with patients with hematocrit >= 29%.

  • 出版日期2017-9-7
  • 单位rutgers