A late Neolithic expansion of Y chromosomal haplogroup O2a1-M95 from east to west

作者：Arunkumar Ganesh Prasad; Wei Lan Hai; Kavitha Valampuri John; Syama Adhikarla; Arun Varatharajan Santhakumari; Sathua Surendra; Sahoo Raghunath; Balakrishnan R; Riba Tomo; Chakravarthy Jharna; Chaudhury Bapukan; Panda Premanada; Das Pradipta K; Nayak Prasanna K; Li Hui; Pitchappan Ramasamy^*

来源：Journal of Systematics and Evolution, 2015, 53(6): 546-560.

DOI：10.1111/jse.12147

• Laos
• migration
• Neolithic
• NRY
• O2a1-M95

The origin and dispersal of Y-Chromosomal haplogroup O2a1-M95, distributed across the Austro Asiatic speaking belt of East and South Asia, are yet to be fully understood. Various studies have suggested either an East Indian or Southeast Asian origin of O2a1-M95. We addressed the issue of antiquity and dispersal of O2a1-M95 by sampling 8748 men from India, Laos, and China and compared them to 3307 samples from other intervening regions taken from the literature. Analyses of haplogroup frequency and Y-STR data on a total 2413 O2a1-M95 chromosomes revealed that the Laos samples possessed the highest frequencies of O2a1-M95 (74% with >0.5) and its ancestral haplogroups (O2*-P31, O*-M175) as well as a higher proportion of samples with 14STR-median haplotype (17 samples in 14 populations), deep coalescence time (5.7 +/- 0.3 Kya) and consorted O2a1-M95 expansion evidenced from STR evolution. All these suggested Laos to carry a deep antiquity of O2a1-M95 among the study regions. A serial decrease in expansion time from east to west: 5.7 +/- 0.3 Kya in Laos, 5.2 +/- 0.6 in Northeast India, and 4.3 +/- 0.2 in East India, suggested a late Neolithic east to west spread of the lineage O2a1-M95 from Laos.

• 出版日期2015-11
• 单位复旦大学