A sulfonate-based Cu(I) metal-organic framework as a highly efficient and reusable catalyst for the synthesis of propargylamines under solvent-free conditions

作者：Li, Peng; Regati, Sridhar; Huang, Hui-Cai; Arman, Hadi D.; Chen, Bang-Lin^*; Zhao, John C. -G.

来源：Chinese Chemical Letters, 2015, 26(1): 6-10.

DOI：10.1016/j.cclet.2014.10.022

• Metal-organic framework
• Heterogeneous catalysis
• Propargylamine
• Solvent-free

A new highly efficient and reusable Cu(I)-MOF has been developed for the synthesis of propargylamine compounds via the three-component reaction of secondary amines, alkynes, and aromatic aldehydes under solvent-free conditions. The desired propargylamines were obtained in good to excellent yields with a low catalyst loading. The catalyst may be recovered and reused for up to 5 cycles without major loss of activity. This protocol has the advantages of excellent yields, low catalyst loading, and catalyst recyclability.

• 出版日期2015-1