A novel approach to phosphonic acids from hypophosphorous acid

作者：Bravo Altamirano Karla; Montchamp Jean Luc^*

来源：Tetrahedron Letters, 2007, 48(33): 5755-5759.

DOI：10.1016/j.tetlet.2007.06.090

• phosphonic acid
• H-phosphinic acid
• hypophosphorous acid

A novel access to phosphonic acids via Pd-catalyzed tandem carbon-phosphorus bond formation-oxidation processes was developed. The procedures involve atom-economical and environmentally friendly functionalization reactions of hypophosphorous acid (H(3)PO(2)) and H-phosphinic acids [RP(O)(OH)(H)].

• 出版日期2007-8-13