A novel biocompatible europium ligand for sensitive time-gated immunodetection

作者:Sayyadi Nima; Connally Russell E; Try Andrew
来源:Chemical Communications, 2016, 52(6): 1154-1157.
DOI:10.1039/c5cc06811h

摘要

We describe the synthesis of a novel hydrophilic derivative of a tetradentate beta-diketone europium ligand that was used to prepare an immunoconjugate probe against Giardia lamblia cysts. We used a Gated Autosynchronous Luminescence Detector (GALD) to obtain high quality delayed luminescence images of cells 30-fold faster than ever previously reported.

  • 出版日期2016