Natural products-based insecticidal agents 20. Design, synthesis and insecticidal activity of novel honokiol/magnolol azo derivatives

作者：Yang, Chun; Zhi, Xiaoyan; Li, Jie; Zha, Jing; Xu, Hui^*

来源：Industrial Crops and Products, 2015, 76: 761-767.

DOI：10.1016/j.indcrop.2015.08.003

• Honokiol
• Magnolol
• Insecticidal activity
• Natural-product-based insecticide
• Structural modification
• Mythimna separata walker

Honokiol and magnolol are small-molecule polyphenols isolated from the barks of Magnolia officinalis. To discover novel natural-product-based pesticidal agents, a series of honokiol/magnolol azo derivatives were prepared by structural modification of honokiol or magnolol. Their insecticidal activity was evaluated at 1 mg/mL against the pre-third-instar larvae of oriental armyworm (Mythimna separata Walker), a typical lepidopteran pest. Among all derivatives, 5m and 6k exhibited more promising insecticidal activity with the final mortality rates greater than 60%, when compared with their precursors (honokiol and magnolol) and the positive control, toosendanin.

• 出版日期2015-12-15
• 单位西北农林科技大学