科研之友
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摘要
Object Current lumbar total disc replacement (TDR) devices require an anterior approach for implantation This approach has inherent limitations including risks to abdominal structures and the need for resection of the an tenor longitudinal ligament (ALL) Placement of a TDR device from a true lateral (extreme lateral interbody fusion [XLIF]) approach is thought to offer a less invasive option to access the disc space preserving the stabilizing ligaments and avoiding scarring of anterior vasculature In this study the authors attempted to quantify the clinical and radiographic outcomes of a lateral approach to lumbar TDR from a prospective single-center experience
Methods A TDR device designed for implantation through a true lateral retroperitoneal transpsoas approach (XLIF) was implanted in 36 patients with discography-confirmed 1 or 2 level degenerative disc disease Clinical (pain and function) and radiographic (range of motion [ROM]) data were prospectively collected preoperatively, postoperatively and serially for a minimum of 24 months follow-up
Results Thirty six surgeries were performed in 16 men and 20 women (mean age 42 6 years) Surgeries included 15 single-level TDR procedures at L3-4 or L4-5, three 2-level TDR procedures spanning L3-4 and L4-5, and 18 hybrid procedures (anterior lumbar interbody fusion [ALIF]) at L5-S1 and TDR at L4-5 [17] or L3-4 [1])
Operative time averaged 130 minutes with an average blood loss of 60 ml and no intraoperative complications Postoperative radiographs showed good device placement All patients were walking within 12 hours of surgery and all but 9 were discharged the next day (7 of 9 had hybrid TDR/ALIF procedures)
Five patients (13 8%) had psoas weakness and 3 (8 3%) had anterior thigh numbness postoperatively both resolving within 2 weeks One patient (2 8%) demonstrated weakness of the leg ipsilateral to the approach side which lasted through the 3 month visit but was resolved by the 6 month visit One patient (2 8%) was found to have hypertrophy of the quadriceps contralateral to the approach side at the 12 month visit, which was resolved by the 2-year visit Four patients (11%) had postoperative facet joint pain, all in hybrid cases
All patients were 2 years or more postsurgery as of this writing, although 3 were lost to follow-up between the 1 and 2-year visits In 2 cases (5 6%) removal of the TDR device and revision to fusion were required due to unresolved pain At 2 years' follow-up the average visual analog scale and Oswestry Disability Index scores had improved 69 6% and 61 4%, respectively and ROM averaged 8 6 degrees, well within physiological norms
Conclusions Long term results of a laterally placed TDR device demonstrate maintenance of pain relief and functional improvement The benefits of this technique-minimal morbidity, avoiding mobilization of the great vessels preserving the ALL biomechanically stable orientation and broader revision options-suggest a promising new direction for TDR procedures (DOI 10 3171/2010 9 SPINE09865)
- 出版日期2011-1
