Molecular folding induced nanogold aggregation

作者：Velu Ranganathan; Ashokkumar Pichandi; Ramakrishnan Vayalakkavoor T; Ramamurthy Perumal^*

来源：Tetrahedron Letters, 2010, 51(23): 3102-3105.

DOI：10.1016/j.tetlet.2010.04.023

• Bisacridinedione
• Photoinduced electron transfer
• Surface plasmon resonance (SPR)
• Nano-Au aggregation
• Fluorescence enhancement

Bisacridinedione-functionalized gold nanoparticles (bisADD-GNPs) were prepared and characterized. Bis-ADD is a flexible acyclic moiety and a specific Ca(2+) sensor. Signaling of the binding events is achieved by the cation-induced folding of the bisADD-GNPs and the resultant fluorescence enhancement and visual color change are attributed to the suppression of photoinduced electron transfer (PET) through space and nano-Au aggregation. The selective binding of Ca(2+) is clear from steady state fluorescence and TEM techniques.

• 出版日期2010-6-9