Sexual transmission of Trypanosoma cruzi in murine model

作者：Ribeiro Marcelle; Nitz Nadjar; Santana Camilla; Moraes Aline; Hagstroem Luciana; Andrade Rafael; Rios Adriano; Sousa Alessandro; Dallago Bruno; Gurgel Goncalves Rodrigo; Hecht Mariana^*

来源：Experimental Parasitology, 2016, 162: 1-6.

DOI：10.1016/j.exppara.2015.12.017

• Trypanosoma cruzi
• Chronic Chagas disease
• Sexual transmission
• Murine model

Trypanosoma cruzi is mainly transmitted by blood-sucking triatomines, but other routes also have epidemiological importance, such as blood transfusion and congenital transmission. Although the possibility of sexual transmission of T. cruzi has been suggested since its discovery, few studies have been published on this subject. We investigated acquisition of T. cruzi by sexual intercourse in an experimental murine model. Male and female mice in the chronic phase of Chagas disease were mated with naive partners. Parasitological, serological and molecular tests demonstrated the parasites in tissues and blood of partners. These results confirm the sexual transmission of T. cruzi in mice.

• 出版日期2016-3