摘要
A siloxy-L-serine organocatalyst has been developed to catalyze direct asymmetric aldol reactions in the presence of water, furnishing the beta-hydroxy carbonyl scaffold in high enantio- and diastereoselectivities. The direct aldol reaction between a selection of aromatic aldehydes and cyclohexanone resulted in good yields and high enantioselectivities.
- 出版日期2007-6-11
- 单位南阳理工学院