Delayed anaphylaxis after ingestion of meat. Carbohydrate epitope galactose-alpha-1,3-galactose as cause of severe anaphylactic reactions

作者：Soemantri S P; Hoextermann S; Holz Larose R; Altmeyer P; Dickel H^*

来源：Hautarzt, 2015, 66(2): 117-120.

DOI：10.1007/s00105-014-3504-x

• Cetuximab
• Mammalian meat
• Food allergy
• Tick bites
• Parasitosis

The correlation between anaphylaxis after consumption of meat and the carbohydrate epitope galactose-alpha-1,3-galactose (alpha-Gal) was first described in oncologic patients treated with cetuximab. An association with tick bites and parasitosis is suspected. We report on a healthy patient who developed sudden anaphylactic reactions after the ingestion of meat. Serologic and skin tests confirmed sensitization to alpha-Gal. Avoiding the consumption of mammalian meat led to a complete absence of symptoms.

• 出版日期2015-2