A Host MicroRNA Brokers Truce with HSV-1

作者:Pare Justin M; Sullivan Christopher S*
来源:Cell Host & Microbe, 2014, 15(4): 395-397.
DOI:10.1016/j.chom.2014.03.011

摘要

Establishing lifelong infection and periodically shedding infectious progeny is a successful strategy employed by several persistent pathogens. In this issue of Cell Host & Microbe, Pan et al. (2014) demonstrate that a cell-type-specific host microRNA can restrict gene expression and pathogenicity of herpes simplex virus 1, thereby promoting long-term infection.

  • 出版日期2014-4-9