Natural history of intradural-extramedullary spinal cord tumors

作者：Ozawa Hiroshi^*; Onoda Yoshito; Aizawa Toshimi; Nakamura Takeshi; Koakutsu Tomoaki; Itoi Eiji

来源：Acta Neurologica Belgica, 2012, 112(3): 265-270.

DOI：10.1007/s13760-012-0048-7

• Spinal cord tumor
• Intradural-extramedullary
• Natural history
• Annual growth rate

The objective of the present study was to investigate the natural history of intradural-extramedullary spinal cord tumors. Nine cases of intradural-extramedullary tumors were observed over the 2 years. The physical and magnetic resonance imaging (MRI) examination were performed in the first examination and every other year. Tumors were classified as the schwannoma type and the meningioma type based on the MRI findings. The tumor volume was calculated by the craniocaudal length on a sagittal image and maximum transverse diameter on an axial image of MRI, every year. The annual growth rate, which was defined as the change in the volume each year compared to the volume of the previous year, was examined. There were six cases in the schwannoma type and three cases in the meningioma type. The schwannoma type tumors presented several growth patterns: unchanging, continuous slight growth, and initial slight growth followed by rapid growth during the observation period (6.7 +/- A 2.7 years), while the meningioma type tumors presented the continuous growth pattern during the observation period (4.3 +/- A 2.5 years). The average annual growth rate was 2.3 +/- A 5.5% in the schwannoma type and 7.0 +/- A 8.5% in the meningioma type. Schwannoma type tumors showed relatively less change in their size and would be observed for a longer time.

• 出版日期2012-9