Higher body mass index in adults at diagnosis of the slowly progressive form of type 1 diabetes mellitus is associated with lower risk HLA genes

作者：Fourlanos S; Elkassaby S; Varney M D; Colman P G; Harrison L C^*

来源：Diabetes Research and Clinical Practice, 2014, 104(3): E69-E71.

DOI：10.1016/j.diabres.2014.03.009

• Type 1 diabetes mellitus
• Body weight
• HLA
• Gene penetrance
• LADA

We hypothesised that higher body weight, a proposed risk factor for type 1 diabetes mellitus, would be associated with increased penetrance of lower risk genes. In adults at diagnosis of the slowly progressive form of type 1 diabetes mellitus we found that higher body mass index was associated with the absence of the highest risk HLA genes.

• 出版日期2014-6
• 单位河北医科大学