3D-printed guiding templates for improved osteosarcoma resection

作者：Ma, Limin; Zhou, Ye; Zhu, Ye; Lin, Zefeng; Wang, Yingjun; Zhang, Yu^*; Xia, Hong^*; Mao, Chuanbin^*

来源：Scientific Reports, 2016, 6(1): 23335.

DOI：10.1038/srep23335

• TUMOR RESECTION
• ASSISTED SURGERY
• LOCAL RECURRENCE
• COMPUTER
• RECONSTRUCTION

Osteosarcoma resection is challenging due to the variable location of tumors and their proximity with surrounding tissues. It also carries a high risk of postoperative complications. To overcome the challenge in precise osteosarcoma resection, computer-aided design (CAD) was used to design patient-specific guiding templates for osteosarcoma resection on the basis of the computer tomography (CT) scan and magnetic resonance imaging (MRI) of the osteosarcoma of human patients. Then 3D printing technique was used to fabricate the guiding templates. The guiding templates were used to guide the osteosarcoma surgery, leading to more precise resection of the tumorous bone and the implantation of the bone implants, less blood loss, shorter operation time and reduced radiation exposure during the operation. Follow-up studies show that the patients recovered well to reach a mean Musculoskeletal Tumor Society score of 27.125.

• 出版日期2016-3-21
• 单位广州军区广州总医院; 华南理工大学; 浙江大学