Steroidal glycosides from the roots of Cynanchum amplexicaule Sieb. et Zucc

作者:Chen, Huan; Xu, Nan; Zhou, Yuzhi; Qiao, Li; Cao, Jiaqing; Yao, Yao; Hua, Huiming; Pei, Yuehu*
来源:Steroids, 2008, 73(6): 629-636.
DOI:10.1016/j.steroids.2008.01.024

摘要

Seven new steroidal glycosides (amplexicosides A (4), B (7), C (8), D (9), E (10), F (11), and G (12)), along with six known compounds (cynatratoside A (1), tylophoside A (2), cynatratoside B (3), glaucogenin A (5), glaucoside A (6), and hancoside A (13)) were isolated from the 95% ethanol extract of the roots of Cynanchum amplexicaule (Sieb. et Zucc.). Their structures were determined based on spectral and chemical evidence. Compound 12 has a 14, 15-secopregnane-type skeleton aglycone, which has not been reported in literature.