Central regulation of reproduction and food-intake: functional asymmetry in the hypothalamus

作者:Istvan Toth*; Sandor Kiss David; Laszlo Frenyo V; Attila Zsarnovszky
来源:Magyar Allatorvosok Lapja, 2017, 139(4): 235-245.

摘要

Background: The hypothalamus is the highest centre and the main crossroad of numerous horneostatic regularity pathways including reproductive and hunger-satiety cycles. Histologically, the left and right hypothalamic sides are symmentrical, still, it has been considered as an unpaired midline structure, in which the identical circuits of the two sides regulate exactly the same biological functions. However, it has been known for higher, morphologically also symentric brain areas that usually the left and right sides have distinct physiological roles providing a solution for the "ergonomic" use of brain resources.
Objectives: The main goal of this article is to shortly sum of our present knowledge on the hypothalmic functions related to the regulation of food-intake and reproduction. Furthermore, the authors also review the asymmetric functions of the central nervous system, in which a special focus is put on the hypothalmus.
Discussion and Conclusion: functions of the central nervous system from the spinal cord to the cerebral cortex are more and more specified to certain functions, and functions show lateralization to different degrees. This evaluationary process of lateralization would provide a much more effective use of brain resources. Based on the presented data in this article, we can use that the hypothalmus, similar to the cortex, shows asymmetric functions, and it seems to be rightful to re-name the hypothalmic sides to hypothalmic hermisphere. This novel aspects on the hypothalmic hemisphere changes our current view on the regulation of female reproduction and food-intake, and provides new perspectives for the better understanding of these hypothalamus-driven physiological processes.

  • 出版日期2017-4