Anti-inflammatory Terpenes from Flowers of Inula japonica

作者:Tang, Sheng-An; Zhu, Hong; Qin, Nan; Zhou, Jing-Ya; Lee, Eunkyung; Kong, De-Xin; Jin, Mei-Hua; Duan, Hong-Quan*
来源:Planta Medica, 2014, 80(7): 583-589.
DOI:10.1055/s-0034-1368353

摘要

Five new terpenes (1-5) and ten known compounds (6-15) were isolated from Inula japonica, and their structures were identified by spectroscopic analysis. Compounds 3 and 14 showed positive inhibitory effects on nitric oxide production. Furthermore, compound 14 suppressed both leukotriene C-4 synthesis and degranulation in c-kit ligand-induced bone marrow-derived mast cells.