Binding Capacity for Aflatoxin B-1 by Different Adsorbents

作者：Li Juan juan; Suo De cheng; Su Xiao ou^*

来源：Agricultural Sciences in China, 2010, 9(3): 449-456.

DOI：10.1016/S1671-2927(09)60116-4

• adsorbent
• AFB1
• absorption efficacy

In this article, in vitro adsorption of aflatoxin B-1 (AFB(1)) onto different adsorbents was characterized and the result was verified by comparing the growth performance and serum protein levels of broilers exposed to aflatoxin-contamination feed. Main components of adsorbents selected were yeast cell extracts (Product A), HSCAS (Product B), and a mixture of yeast product and HSCAS (Product C), respectively. A total of 240 broilers were assigned to eight treatments, and the effects of three types of adsorbents on growth performance and serum protein levels were evaluated. Results indicated that Product B had the highest in vitro affinity for AFB(1), followed by Product C and Product A. Product B bound 97.69% of the AFB1 in solution in 10 min, and it remained over 96.03% in 60 min at pH 8.0. The B-AFB(1) complex was much stronger than the other two complexes in vitro condition (P < 0.05). Feed intake (FI) and average daily gain (ADG) decreased (P < 0.05) and feed gain ratio increased (P < 0.05) in the treatment fed aflatoxin-contaminated feed versus treatment on the basal feed. Serum total protein (TP), albumin (ALB), and globulin (GLOB) levels were significantly decreased (P < 0.05). Product B (0.15%) increased growth performance and improved serum protein levels, Product A and Product C were not as effective as Product B. Three adsorbents tested here had sufficient potential to AFB(1) in some extents and Product B could bind AFB(1) more effectively than Product A and Product C. These results indicated that Product B could alleviate some of the AFB(1) toxic effect in broilers.

• 出版日期2010-3
• 单位中国农业科学院