Hybrid supramolecular hydrogels induced by Au nanoparticles protected with MPEG- b- PCL copolymers with alpha-cyclodextrin

作者：Zhao Sanping^*; Zhou Feng; Liu Ruina

来源：Supramolecular Chemistry, 2013, 25(12): 767-776.

DOI：10.1080/10610278.2013.803107

• Au nanoparticle
• supramolecular hydrogel
• self-assembled monolayer
• -cyclodextrin
• inclusion complexation

To fabricate supramolecular hydrogel hybridised with well-dispersed gold nanoparticles (AuNPs), water-soluble AuNPs protected with methoxy poly(ethylene glycol)-b-poly(E-caprolactone) (MPEG-b-PCL) self-assembled monolayers (MPEG-b-PCL/AuNPs) were synthesised and used as guest molecules to interact with -cyclodextrin (-CD) in aqueous solutions. Transmission electron microscopy measurement results showed that the diameter of the AuNPs produced was about 6-10nm with a narrow particle size distribution, and stained MPEG-b-PCL/AuNPs micelles made in water clearly displayed the formation of a core-shell structure with a single gold core per micelle. X-ray diffraction measurement results confirmed that there existed the characteristic peaks of both AuNPs and polypseudorotaxanes formed via the inclusion complexation of MPEG-b-PCL moieties with -CD in as-obtained hydrogels. UV-visible spectra displayed that the same surface plasma resonance absorption peaks appeared at 526nm for both aqueous dispersion of MPEG-b-PCL/AuNPs and resultant hybrid hydrogel with -CD. Rheological measurements showed that the hybrid hydrogel has a lower mechanical strength and viscosity, and a relatively prolonged gelation time in comparison with the corresponding native hydrogel. The mechanical strength of the hydrogel nanocomposites could be tailored by modulating the concentration of MPEG-b-PCL/AuNPs and -CD as well as the composition of MPEG-b-PCL/AuNPs.

• 出版日期2013-12-1
• 单位武汉纺织大学