Aliphatic Ketones from Ruta chalepensis (Rutaceae) Induce Paralysis on Root Knot Nematodes

作者：Ntalli Nikoletta G; Manconi Francesca; Leonti Marco; Maxia Andrea; Caboni Pierluigi^*

来源：Journal of Agricultural and Food Chemistry, 2011, 59(13): 7098-7103.

DOI：10.1021/jf2013474

• GC-MS
• LC-MS
• Ruta chalepensis
• ketones
• 2-undecanone
• Meloidogyne incognita
• Meloidogyne javanica

This paper reports on the use of Ruta chalepensis L. extracts as a potential nematicide against root knot nematodes Meloidogyne incognita and Meloidogyne javanica. The essential oil (REO) and methanol extract (RME) of R. chalepensis were tested against second-stage juveniles, with REO inducing paralysis in both species (EC(50/1d) = 77.5 and 107.3 mg/L) and RME being selective for M. incognita (EC(50/1d) = 1001 mg/L). Chemical characterization of extracts was done by means of GC-MS and LC-MS, revealing mainly aliphatic ketones and coumarins, respectively. The first-ranking volatile nematicidal component in terms of individual activity against both species was 2-undecanone (EC(50) = 206 and 22.5 mg/L for M. incognita and M javanica, respectively). This fact together with its high concentration in the most active extract found in this study, namely, REO (2926 mg/kg), categorizes 2-undecanone among the nematicidal principles of R chalepensis. On the contrary, coumarins rutin and 8-methoxypsoralen were not found to be nematicidal at concentrations of <= 500 mg/L. Interestingly, M incognita was found more sensitive than M javanica.

• 出版日期2011-7-13