Access to 3-Arylindoles through a Tandem One-Pot Protocol Involving Dearomatization, a Regioselective Michael Addition Reaction, and Rearomatization

作者：Chittimalla Santhosh Kumar^*; Bandi Chennakesavulu; Putturu Sireesha; Kuppusamy Rajesh; Boellaard Kevin Christopher; Tan David Chu Aan; Lum Demi Ming Jie

来源：European Journal of Organic Chemistry, 2014, 2014(12): 2565-2575.

DOI：10.1002/ejoc.201400079

• Synthetic methods
• Domino reactions
• Michael addition
• Nitrogen heterocycles
• Quinones

A facile, general and rapid protocol for the introduction of oxygenated aryls at the 3-position of indoles is described. This approach consists of a tandem dearomatization, a regioselective Michael addition reaction, and rearomatization in a one-pot three-step sequence to obtain 3-arylindoles in good yields.

• 出版日期2014-4