A Monolithically Integrated Pressure/Oxygen/Temperature Sensing SoC for Multimodality Intracranial Neuromonitoring

作者：Chan Wai Pan^*; Narducci Margarita; Gao Yuan; Cheng Ming Yuan; Cheong Jia Hao; George Arup K; Cheam Daw Don; Leong Siew Chong; Damalerio Maria Ramona B; Lim Ruiqi; Tsai Ming Ling; Rahman Abdur R A; Park Mi Kyoung; Kong Zhi Hui; Prashanth Rao Jai; Je Minkyu

来源：IEEE Journal of Solid-State Circuits, 2014, 49(11): 2449-2461.

DOI：10.1109/JSSC.2014.2345754

• Capacitance to voltage converter (CVC)
• capacitive pressure sensor
• electrochemical oxygen sensor
• intracranial pressure (ICP)
• temperature sensor
• traumatic brain injury (TBI)

A fully integrated SoC for multimodality intracranial neuromonitoring is presented in this paper. Three sensors including a capacitive MEMS pressure sensor, an electrochemical oxygen sensor and a solid-state temperature sensor are integrated together in a single chip with their respective interface circuits. Chopper stabilization and dynamic element matching techniques are applied in sensor interface circuits to reduce circuit noise and offset. On-chip calibration is implemented for each sensor to compensate process variations. Measured sensitivity of the pressure, oxygen, and temperature sensors are 18.6 aF/mmHg, 194 pA/mmHg, and 2 mV/degrees C, respectively. Implemented in 0.18 mu m CMOS, the SoC occupies an area of 1.4 mm x 4 mm and consumes 166 W DC power. A prototype catheter for intracranial pressure (ICP) monitoring has been implemented and the performance has been verified with ex vivo experiment.

• 出版日期2014-11
• 单位南阳理工学院