Discovery of potent, novel antibacterial hybrid conjugates from 4-aminoquinoline and 1,3,5-triazine: design, synthesis and antibacterial evaluation

作者：Bhat Hans Raj^*; Gupta Satish Kumar; Singh Udaya Pratap

来源：RSC Advances, 2012, 2(33): 12690-12695.

DOI：10.1039/c2ra22353h

A series of hybrid 4-aminoquinoline-1,3,5-triazine conjugates 7a-g were synthesized and evaluated for their in vitro antibacterial activity against several Gram-positive and Gram-negative micro-organisms. The entire set of target compounds displayed potent to excellent activity against human disease causing pathogens with reference to Levofloxacin as a standard drug.

• 出版日期2012