Steric and substituent effects on the photo reversibility of novel indolospirobenzopyrans: Acid deuterolysis, UV and H-1 NMR spectroscopy

作者：Roxburgh Craig J^*; Sammes Peter G; Abdullah Ayse

来源：Dyes and Pigments, 2009, 82(2): 226-237.

DOI：10.1016/j.dyepig.2009.01.006

• Spirobenzopyrans
• Synthesis
• Photoreversible
• Acid deuterolysis
• UV and H-1 NMR spectroscopy

The photoreversibility, of several novel indolospirobenzopyrans was investigated using temperature studies - monitored using H-1 NMR spectroscopy, qualitative UV studies and acid deuterolysis (trifluorodeuterioacetic acid (TFA-D)) catalysed isomerisation studies. Derivatives that contained appropriately placed electronically modifying substituents on both the indole and benzopyran-rings; also variants possessing sterically hindering (with regard to spiropyran-opening - closing reaction) groups, within the spirocyclic ring-system were prepared. In addition, compounds that contained both sterically restricting and electronically biasing substituents, were investigated, simultaneously.

• 出版日期2009-8
• 单位中国人民解放军海军医学研究所