Macular changes detected by Fourier-domain optical coherence tomography in patients with hypotony without clinical maculopathy

作者：Lima Veronica C; Prata Tiago S; Castro Dinorah P E; Castro Leonardo C; De Moraes Carlos G V; Mattox Cynthia; Rosen Richard B; Liebmann Jeffrey M; Ritch Robert^*

来源：Acta Ophthalmologica, 2011, 89(3): e274-e277.

DOI：10.1111/j.1755-3768.2009.01719.x

• FD-OCT
• hypotony maculopathy
• macular changes
• postoperative hypotony

Purpose:
To investigate macular changes in eyes with postoperative hypotony without clinical maculopathy using high-resolution Fourier-domain optical coherence tomography (FD-OCT).
Methods:
Fourteen eyes of 12 patients with postoperative intraocular pressure (IOP) < 6 mmHg for at least 4 weeks but with no detectable clinical features associated with hypotony maculopathy were imaged by FD-OCT prospectively. Images were analysed by two retina specialists masked to clinical findings.
Results:
Most patients were female (83%) and myopic (75%) with a mean age of 65 +/- 17 [standard deviation (SD)] years (range 2-86 years). Mean central corneal thickness was 519 +/- 34 mu m [95% confidence interval (CI) 502-537] and mean IOP before surgery was 20 +/- 8 mmHg (95% CI 15-24). During the period of hypotony (mean 15 +/- 6 weeks), the average mean IOP was 4 +/- 1 mmHg (95% CI 3-5). Abnormal FD-OCT findings (retinal folds and/or intraretinal fluid) were present in eight eyes. These patients had a higher rate of visual symptoms (75% versus 17%), visual acuity loss (>= 2 lines; 63% versus 17%) and increased mean foveal thickness (250 +/- 26 versus 210 +/- 12 mu m; p < 0.01, Mann-Whitney U-test) compared with those with normal FD-OCT.
Conclusion:
FD-OCT identified subclinical macular abnormalities in over half of the eyes with postoperative hypotony. These findings were accompanied by visual disturbances and central macular thickening. FD-OCT can be an important diagnostic tool for this disorder when clinical features are absent.

• 出版日期2011-5