A water wire in L-prolyl-L-serine monohydrate

作者：Gorbitz Carl Henrik^*; Yadav Vitthal N

来源：Acta Crystallographica Section C-Crystal Structure Communications, 2013, 69: 556-+.

DOI：10.1107/S0108270113010299

Despite the extra functional group in the serine side chain, the crystal packing arrangement of the title compound {systematic name: (S)-3-hydroxy-2-[(S)-pyrrolidine-2-carboxamido]propanoic acid monohydrate}, C8H14N2O4H2O, is essentially the same as observed for a series of L-Pro-L-Nop peptide hydrates, where Nop is a strictly nonpolar residue. This is rendered possible by a monoclinic P21 packing arrangement with Z = 2 that deviates from orthorhombic P212121 symmetry only for the seryl hydroxy groups, which form infinite OH...OH hydrogen-bonded chains along the 5.3 angstrom a axis. At the same time, cocrystallized water molecules form parallel water wires.

• 出版日期2013-5